Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis

Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis

BACKGROUND There are increasing studies examining the relationship between the status of H. pylori oipA gene and peptic ulcer disease (PUD) and gastric cancer (GC) but the results turn out to be controversial. We attempted to clarify whether oipA gene status is linked with PUD and/or GC risks. METHODS A systematically literature search was performed through four electronic databases. Accordin...

THE ASSOCIATION OF CAMPYLOBACTER PYLORI (HELICOBACTER PYLORI) WITH GASTRITIS AND PEPTIC ULCER

We studied the relationship between gastroduodenal inflammation and the presence of Campylobaeter pylori from biopsy specimens of the gastric mucosa in 91 patients with gastritis with or without ulcers and 9 controls, healthy or suffering from other diseases. 68 of the patients were positive for the presence of C. pylori in their gastric mucosa. C. pylori was confirmed bacteriohistological...

Author's response to reviews Title: Association of presence/absence and on/off patterns of Helicobacter pylori oipA gene with peptic ulcer disease and gastric cancer risks: a meta-analysis Authors:

Helicobacter pylori infection in peptic ulcer disease and gastric malignancy.

Helicobacter pylori infection is the world's most common chronic infection in humans and is the cause of most gastritis cases. This infection is accepted as the etiology of the majority of peptic ulcers. It has been implicated as a significant contributing factor in the development of gastric malignancy--both gastric MALT lymphoma and gastric adenocarcinoma. Both endoscopic and non-endoscopic t...

Helicobacter pylori, peptic ulcer and gastric cancer in China.

INTRODUCTION Recent epidemiological evidence supports a strong relationship between Helicobacter pylori infection and gastric cancer [1-11]. The relative risk for cancer with an infection of five years and over is in the region of three to six (Table 1). The identification of almost universal coexistence of H. pylori related antral gastritis in patients with duodenal ulcer disease [12, 13] and ...